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Drug Dependence Hydromorphone Hydrochloride Injection can produce drug dependence of the morphine type and therefore has the potential for being abused.Impaired Respiration Respiratory depression is the chief hazard of Hydromorphone Hydrochloride Injection.Respiratory depression occurs most frequently in the elderly, in the debilitated, and in those suffering from conditions accompanied by hypoxia or hypercapnia when even moderate therapeutic doses may dangerously decrease pulmonary ventilation.

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For example: The presence/absence of ascites, lymphadenopathy or distant metastases should be noted in cases of known primary carcinomas.

It may be appropriate, depending on local practice, to suggest further investigations which may clarify the diagnosis. Gestation sac volume 0.4mls, equivalent to 5 weeks. Normal appearances with measurements in agreement with recent positive pregnancy test.

PLEASE READ THE Inspect parenteral drug products visually for particulate matter and discoloration prior to administration, whenever solution and container permit. Infants born to mothers physically dependent on Hydromorphone Hydrochloride Injection will also be physically dependent and may exhibit respiratory difficulties and withdrawal symptoms.

Psychic dependence, physical dependence and tolerance may develop upon repeated administration of Hydromorphone Hydrochloride Injection and it should be prescribed and administered with the same degree of caution appropriate for the use of morphine.

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